This piece was co-written with Rik Renard, who shares weekly insights on healthcare AI and strategy on LinkedIn.
One fascinating thing we read this week was a story about the GitLab founder who went "founder mode" on his cancer. Now it's no longer detectable.
After standard treatment failed, Sid Sijbrandij built a 1,000-page health handbook, ran every diagnostic available, and assembled a SWAT team to design personalized treatments in parallel instead of waiting for each one to fail sequentially.
Elliot Hershberg - a fantastic fellow creator - wrote a great piece on this.
What stands out isn't just what happened, but what's technically possible right now. Sid is a billionaire with a full-time team, so this isn't replicable for 99.9% of patients today. But it's a glimpse of where we could be heading.
The diagnostics exist. The personalized therapies exist. The bottleneck isn't the science, it's the system and the cost. Sid had to hire people just to get access to his own tissue samples. He had to file special applications to access experimental drugs that exist but aren't available through normal channels.
Which brings up something bigger: physicians need a mindset shift too. Treatment pathways can't be hard-coded in PDFs and updated every 18 months anymore. With new therapies emerging constantly*, oncology needs to move toward continuous iteration. AI-enabled tools like OpenEvidence, UpToDate, and others are enabling this iterative future. Kinda scary but also very promising.
The question: will AI make this type of personalized approach feasible without requiring billions? Or will the gap between what's possible and what's accessible keep growing?
Worth thinking about as we build the future of healthcare.
PS: Sid also started 8 companies in the oncology space to help other patients. So maybe it's closer than we think!
Note: Obviously patients aren't guinea pigs, new therapies need proper evidence and validation. But the pace of iteration can and should be faster than it is today.